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Protect Yourself From a Lapse in Coverage

Alpha-1 Therapy

For every month in which you use Zemaira® Alpha1-Proteinase Inhibitor (Human), regardless of the number of prescriptions filled, you will earn 1 Assurance point.

If you have been enrolled for at least 3 months, or earned at least 3 points, by the time of your insurance lapse, you will be eligible to redeem your points as follows:

Multiple points (in increments of 3) may be redeemed within 1 month for a 30-day prescription refill. The number of points that may be redeemed for 1 prescription cannot exceed 12.

Please review the program Terms and Conditions for a complete description of CSL Behring Assurance.

Important Safety Information for Zemaira

Alpha1-Proteinase Inhibitor (Human), Zemaira® is indicated to raise the plasma level of alpha1-proteinase inhibitor (A1-PI) in patients with A1-PI deficiency and related emphysema. The effect of this raised level on the frequency of pulmonary exacerbations and the progression of emphysema have not been established in clinical trials.

Zemaira may not be suitable for everyone; for example, people with known hypersensitivity to components used to make Zemaira, those with a history of anaphylaxis or severe systemic response to A1-PI products, and those with certain IgA deficiencies. If you think any of these may apply to you, ask your doctor.

Early signs of hypersensitivity reactions to Zemaira include hives, rash, tightness of the chest, unusual breathing difficulty, wheezing, and feeling faint. Immediately discontinue use and consult with physician if such symptoms occur.

In clinical studies, the following adverse reactions were reported in at least 5% of subjects receiving Zemaira: headache, sinusitis, upper respiratory infection, bronchitis, fatigue, increased cough, fever, injection-site bleeding, nasal symptoms, sore throat, and swelled blood vessels.

Because Zemaira is made from human blood, the risk of transmitting infectious agents, including viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent, cannot be completely eliminated.

Please see full prescribing information for Zemaira.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.